Headlines

Congratulations to Melinda Simon and Arlene Doria for each winning a poster award at EMBS Micro and Nanotechnology in Medicine Conference, Maui MNM Conference.December, 2012

Congratulations to Yu-Hsiang (Shawn) Hsu for getting the issue 1, 2013 cover of Lab on a Chip with his excellent work: Full range physiological mass transport control in 3D tissue cultures". Art work by the amazing Kanaka! Lab on a ChipOctober 22, 2012

Congratulations to Arlene Doria in winning one of four poster awards of the ~600 posters at the Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences MicroTAS 2012.October, 2012

Congratulations to Melinda Simon who was chosen as this year's ARCS Fellowship recipient for The Henry Samueli School of Engineering. The ARCS Fellowship rewards our most academically superior doctoral students who exhibit outstanding promise. September 24, 2012

Dr. Steven C. George receives NIH funds to develop tissue chips to help predict drug safety. Dr. Abe Lee is included as one of the eight team members in this investigation for his expertise in microfluidics and microfabrication. Headline.July 24, 2012

In collaboration with Abe Lee's group, Antigen Discovery Inc. is awarded a phase I SBIR grant to develop a fully integrated, microfluidic point of care device. Market Watch.Aug 15, 2012

Congratulations to David Bardin in winning a poster award at the 4th International Symposium on Microchemistry and Microsystems ISMM.June 13, 2012

Mindy Simon's Laplace trap paper was the 10th most downloaded from the biomicrofluidics website for March. Biomicrofluidics.March 2012

Shia-Yen Teh's paper on lipid spheres has been selected for the December 15, 2011 issue of : Virtual Journal of Biological Physics Research.January 4, 2012

Shia-Yen Teh's work on a new device that creates lipid spheres that mimic cell membranes is highlighted in : Medical Daily and NanoWerk, December 16, 2011

During the month of October, Andrew Hatch's "1-Million droplet array with wide-field fluorescence imaging for digital PCR" was amongst the top ten accessed articles from the online version of Lab on a Chip. : Access Article, November 28, 2011

Maulik Patel's videos of on-chip cell/particle switches using air-liquid cavity acoustic transders is highlighted in LOC YouTube Videos on the RSC Publishing, Lab on a Chip Blog: LOC Youtube Video, November 22, 2011

David Bardin's work with droplets is a hot article on Lab on a Chip and is highlighed on RSC's blog: Lab on a Chip Blog, November 11, 2011

Integrative Graduate Education and Research Traineeship highlights David Bardin's work with droplets: New Approach in Tumor Imaging, October 24, 2011

Royal Society of Chemistry features our work with droplets in a Chemistry World article: Bubble trouble eliminated in cancer treatment, October 20, 2011

GenomeWeb features our work with droplet arrays in a PCR Insider article : UC Irvine Team Details 1M-Droplet Array for Digital PCR, Claims Advantages over Other Methods, October 20, 2011

The Genetic Engineering Biotechnology News (GEN) magazine features MF3 article: MF3 Fosters Micro/Nanofluidic Collaborations, April 1, 2011

SPIE Publishing Microfluidics Feature Interview: Microfluidics streamlines laboratory operations, December 7, 2010

UCI Irvine Announcement: The Henry Samueli School of Engineering announced that Dr. Abe Lee has been named the new chair of the Department of Biomedical Engineering, April 12, 2010

Archived Laboratory News

Thank you for visiting the Biomolecular Microsystems and Nanotransducers (BioMiNT) in the Biomedical Engineering Department, University of California at Irvine. Our focus is in developing the microscale and nanoscale platform technologies for the interrogation and manipulation of biological and physiological activities. We strongly believe the future of biotechnology and biomedicine to be driven by instruments and devices that can function at the scale of the critical biological elements.

By building on the broad technological base of microsystems technologies (MEMS, microfluidics, micro-optics, biosensors, microelectronics), integration of multifunctional components and interface to the operator is established. The microscale allows devices that are either implantable or can serve as interventional tools to access essentially any part of the human anatomy minimally invasively. The development of microfluidic processors for the integration of sample collection, sample transport, sample preparation, and sample detection requires novel platforms for the sensing and actuation of a wide range of biological species. It is ultimately critical to develop on these microsystems nanoscale interfaces to biological molecules, including nucleic acids, proteins, lipids, and various small molecules.

We are focusing our efforts on two main microsystem platform technologies, controlled micro/nano droplet generation and micro electrofluidic (e.g. MHD, DEP) systems. The applications of our research include the directed synthesis of drug release micro/nano particles, digital bioassays in droplets for point-of-care diagnostics, artificial cells for protein synthesis and biomolecular power harvesting, directed differentiation of neural stem cells, high throughput combinatory screening in droplets, and most recently the development of microtools for interventional neuroradiology.

Regardless of whether it is the microscale or the nanoscale that we exploit, it is ultimately the meter scale (human body) that counts!! It is our sincerest hope that the technology we develop will fundamentally change the way healthcare is practiced today in terms of lower cost, greater accessibility, more individual control, broader distribution, and increased options for every walk of life.

Please direct any academic inquiries to Dr. Abraham P. Lee.