NSF I/UCRC Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM) is officially launched with 13 Industrial Advisory Board (IAB) Members (see press release).
Congratulations to Roger Shih, who was selected as a finalist in the doctoral student poster competition (18 out of 80) at the ASME 2014 3rd Global Congress on NanoEngineering for Medicine and Biology (NEMB2014) .
Through MF3 we are launching a new National Science Foundation (NSF) Industry/University Cooperative Research Center (I/UCRC) entitled “Center for Advanced Design and Manufacturing of Integrated Microfluidics (CADMIM).” The kick-off Industrial Advisory Board Meeting will be held April 10-11. Please visit the CADMIM website for more information: www.inrf.uci.edu/cadmim.
Our recent Biomicrofluidics paper on high speed droplet generation is a top 20 download for the month of July (2013)
Congratulations to Melinda Simon and Arlene Doria for each winning a poster award at EMBS Micro and Nanotechnology in Medicine Conference, Maui MNM Conference.December, 2012
Congratulations to Yu-Hsiang (Shawn) Hsu for getting the issue 1, 2013 cover of Lab on a Chip with his excellent work: Full range physiological mass transport control in 3D tissue cultures". Art work by the amazing Kanaka!
Lab on a ChipOctober 22, 2012
Congratulations to Arlene Doria in winning one of four poster awards of the ~600 posters at the Sixteenth International Conference on Miniaturized Systems for Chemistry and Life Sciences MicroTAS 2012.October, 2012
Congratulations to Melinda Simon who was chosen as this year's ARCS Fellowship recipient for The Henry Samueli School of Engineering. The ARCS Fellowship rewards our most academically superior doctoral students who exhibit outstanding promise.
September 24, 2012
Dr. Steven C. George receives NIH funds to develop tissue chips to help predict drug safety. Dr. Abe Lee is included as one of the eight team members in this investigation for his expertise in microfluidics and microfabrication.
Headline.July 24, 2012
In collaboration with Abe Lee's group, Antigen Discovery Inc. is awarded a phase I SBIR grant to develop a fully integrated, microfluidic point of care device.
Market Watch.Aug 15, 2012
Congratulations to David Bardin in winning a poster award at the 4th International Symposium on Microchemistry and Microsystems
ISMM.June 13, 2012
Mindy Simon's Laplace trap paper was the 10th most downloaded from the biomicrofluidics website for March.
Shia-Yen Teh's paper on lipid spheres has been selected for the December 15, 2011 issue of :
Virtual Journal of Biological Physics Research.January 4, 2012
Shia-Yen Teh's work on a new device that creates lipid spheres that mimic cell membranes is highlighted in :
Medical Daily and
NanoWerk, December 16, 2011
During the month of October, Andrew Hatch's "1-Million droplet array with wide-field fluorescence imaging for digital PCR" was amongst the
top ten accessed articles from the online version of Lab on a Chip. :
Access Article, November 28, 2011
Maulik Patel's videos of on-chip cell/particle switches using air-liquid cavity acoustic transders is highlighted in LOC YouTube Videos on
the RSC Publishing, Lab on a Chip Blog:
LOC Youtube Video, November 22, 2011
David Bardin's work with droplets is a hot article on Lab on a Chip and is highlighed on RSC's blog:
Lab on a Chip Blog, November 11, 2011
Integrative Graduate Education and Research Traineeship highlights David Bardin's work with droplets:
New Approach in Tumor Imaging, October 24, 2011
Royal Society of Chemistry features our work with droplets in a Chemistry World article:
Bubble trouble eliminated in cancer treatment, October 20, 2011
GenomeWeb features our work with droplet arrays in a
PCR Insider article :
UC Irvine Team Details 1M-Droplet Array for Digital PCR, Claims Advantages over Other Methods, October 20, 2011
The Genetic Engineering Biotechnology News (GEN) magazine features MF3 article: MF3 Fosters Micro/Nanofluidic Collaborations, April 1, 2011
SPIE Publishing Microfluidics Feature Interview: Microfluidics streamlines laboratory operations, December 7, 2010
UCI Irvine Announcement: The Henry Samueli School of Engineering announced that Dr. Abe Lee has been named the new chair of the Department of Biomedical Engineering, April 12, 2010
you for visiting the Biomolecular Microsystems and Nanotransducers
(BioMiNT) in the Biomedical Engineering Department, University of
California at Irvine. Our focus is in developing the microscale
and nanoscale platform technologies for the interrogation and manipulation
of biological and physiological activities. We strongly believe
the future of biotechnology and biomedicine to be driven by instruments
and devices that can function at the scale of the critical biological
building on the broad technological base of microsystems technologies
(MEMS, microfluidics, micro-optics, biosensors, microelectronics),
integration of multifunctional components and interface to the operator
is established. The microscale allows devices that are either implantable
or can serve as interventional tools to access essentially any part
of the human anatomy minimally invasively. The development of microfluidic
processors for the integration of sample collection, sample transport,
sample preparation, and sample detection requires novel platforms
for the sensing and actuation of a wide range of biological species.
It is ultimately critical to develop on these microsystems nanoscale
interfaces to biological molecules, including nucleic acids, proteins,
lipids, and various small molecules.
are focusing our efforts on two main microsystem platform technologies,
controlled micro/nano droplet generation and micro electrofluidic
(e.g. MHD, DEP) systems. The applications of our research include
the directed synthesis of drug release micro/nano particles, digital
bioassays in droplets for point-of-care diagnostics, artificial
cells for protein synthesis and biomolecular power harvesting, directed
differentiation of neural stem cells, high throughput combinatory
screening in droplets, and most recently the development of microtools
for interventional neuroradiology.
of whether it is the microscale or the nanoscale that we exploit,
it is ultimately the meter scale (human body) that counts!! It is
our sincerest hope that the technology we develop will fundamentally
change the way healthcare is practiced today in terms of lower cost,
greater accessibility, more individual control, broader distribution,
and increased options for every walk of life.
Please direct any academic inquiries to Dr.
Abraham P. Lee.