PI: Prof. Abe Lee
News about our latest publication: Researchers develop process producing cell-sized lipid vesicles for cell-cell synaptic therapies
Editorial by Prof. Abe Lee: "Lab on a Chip in 2017", Lab Chip, 2018, 18, 9-10
Prof. Abe Lee chairs MicroTAS 2017 in Savannah, Georgia - 9 BioMiNT papers were presented, 2 oral and 7 posters.
Our paper on a "High Throughput Microfluidic Platform for Size-Selective Enrichment of Cell Populations in Tissue and Blood Samples" is featured as cover image for the journal Analyst
Congratulations to Xuan Li for receiving one of the Podium Presentation Awards at the 18th Annual UC Systemwide Bioengineering Symposium, held at UCLA June 28-30, 2017
Our recent "Lego Microfluidics" paper published in JMM is featured in IOP and 3D Printing Industry
Professor Abe Lee is announced as the new Lab on a Chip Editor-in-Chief also read at RSC blog
you for visiting the Biomolecular Microsystems and Nanotransducers
(BioMiNT) in the Biomedical Engineering Department, University of
California at Irvine. Our focus is in developing the microscale
and nanoscale platform technologies for the interrogation and manipulation
of biological and physiological activities. We strongly believe
the future of biotechnology and biomedicine to be driven by instruments
and devices that can function at the scale of the critical biological
building on the broad technological base of microsystems technologies
(MEMS, microfluidics, micro-optics, biosensors, microelectronics),
integration of multifunctional components and interface to the operator
is established. The microscale allows devices that are either implantable
or can serve as interventional tools to access essentially any part
of the human anatomy minimally invasively. The development of microfluidic
processors for the integration of sample collection, sample transport,
sample preparation, and sample detection requires novel platforms
for the sensing and actuation of a wide range of biological species.
It is ultimately critical to develop on these microsystems nanoscale
interfaces to biological molecules, including nucleic acids, proteins,
lipids, and various small molecules.
are focusing our efforts on two main microsystem platform technologies,
controlled micro/nano droplet generation and micro electrofluidic
(e.g. MHD, DEP) systems. The applications of our research include
the directed synthesis of drug release micro/nano particles, digital
bioassays in droplets for point-of-care diagnostics, artificial
cells for protein synthesis and biomolecular power harvesting, directed
differentiation of neural stem cells, high throughput combinatory
screening in droplets, and most recently the development of microtools
for interventional neuroradiology.
of whether it is the microscale or the nanoscale that we exploit,
it is ultimately the meter scale (human body) that counts!! It is
our sincerest hope that the technology we develop will fundamentally
change the way healthcare is practiced today in terms of lower cost,
greater accessibility, more individual control, broader distribution,
and increased options for every walk of life.
Please direct any academic inquiries to Dr.
Abraham P. Lee.