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Education:
- Ph.D., Biomedical
Engineering, University of California, Irvine
- M.S., Biomedical
Engineering, University of California, Irvine
- B.S.,
Bioengineering, University of California, San Diego
Journal
Publications:
- Kanaka Hettiarachchi, Steven Feingold, Shirley Zhang, Abraham P. Lee, Paul A. Dayton. "Controllable Microfluidic Synthesis of Multiphase Drug-Carrying Lipospheres for Site-Targeted Therapy", Biotechnology Progress, vol. 25 (4), pp. 938 - 945, 2009
- Esra Talu, Kanaka Hettiarachchi, Robert L. Powell, Abraham. P. Lee, Paul
A. Dayton, Marjorie L. Longo, “Maintaining Monodispersity
in a Microbubble Population Formed by Flow Focusing”, Langmuir, vol. 24 (5), pp. 1745-1749, 2008
- Esra
Talu, Kanaka Hettiarachchi, Shukui Zhao, Robert L. Powell, Abraham.
P. Lee, Marjorie L. Longo, Paul A. Dayton, “Tailoring
the size distribution of ultrasound contrast agents: A possible
method for improving sensitivity in molecular imaging”,
Molecular Imaging, vol. 6 (6), pp. 384-392, 2007
- Kanaka
Hettiarachchi, Esra Talu, Marjorie L. Longo, Paul A. Dayton, and
Abraham P. Lee*, "On-chip generation of microbubbles
as a practical technology for manufacturing contrast agents for
ultrasonic imaging", Lab on a Chip, vol.
7(4), pp. 463-468, 2007
- Yung-Chieh
Tan, Kanaka Hettiarachchi, Maria Siu, Yen-Ru Pan, and Abraham
Phillip Lee, "Controlled Microfluidic Encapsulation
of Cells, Proteins and
Microbeads in Lipid Vesicles", Journal of the
American Chemical Society, vol. 128(17), pp. 5656 - 5658,
2006
Conference
Publications:
- Kanaka Hettiarachchi, Paul A. Dayton, Abraham P. Lee,
“Multimodal Particles for Biological Detection and Therapy”, The Twelth International Conference on Miniaturized Systems
for Chemistry and Life Sciences (uTAS 2008), p. 1765-1767, San Diego, CA, USA, October 12-16, 2008
- Kanaka Hettiarachchi and Abraham P. Lee,
“Venturi-Based Two-Layer Microfluidic Pumping System”, The Twelth International Conference on Miniaturized Systems
for Chemistry and Life Sciences (uTAS 2008), p. 101-103, San Diego, CA, USA, October 12-16, 2008
- Kanaka Hettiarachchi, Paul A. Dayton, Abraham P. Lee, “Lipid-Stabilized Microbubbles for Biomedical Imaging and Targeted Drug Delivery”, 9th Annual UC Systemwide Bioengineering Symposium at UCR, pp. 65, California, USA, June 20-22, 2008
- Esra Talu, Kanaka Hettiarachchi, Shukui Zhao, Robert L. Powell, Abraham P. Lee, Marjorie L. Longo, Paul Dayton, “Monodisperse Microbubble Contrast Agents for Improved Ultrasound Contrast Imaging”, AIChE 2007 Annual Meeting, Salt Lake City, Utah, USA, November 4-9, 2007
- Kanaka
Hettiarachchi, Esra Talu, Marjorie L. Longo, Paul A. Dayton, Abraham
P. Lee, “Manufacture of Dual-Layer Microbubble Lipospheres
as Drug Delivery Vehicles in Microfluidic Devices”,
The Eleventh International Conference on Miniaturized Systems
for Chemistry and Life Sciences (uTAS 2007), pp.
191-193,
Paris, France, October 7-11, 2007 *Best
Poster Award*
- Kanaka Hettiarachchi,
Esra Talu, Marjorie L. Longo, Paul A. Dayton, Abraham P. Lee,
“Multi-Array Flow-Focusing Devices to Accelerate
Production of Microbubbles for Contrast-Enhanced Ultrasound Imaging”,
The Eleventh International Conference on Miniaturized Systems
for Chemistry and Life Sciences (uTAS 2007), pp.
664-666,
Paris, France, October 7-11, 2007
- Abraham P. Lee and Kanaka Hettiarachchi, “Medicine on a Chip – Opportunities for BME Research and Education”, The 3rd WACBE World Congress on Bioengineering 2007, Bangkok, Thailand, July 9-11, 2007
- Kanaka
Hettiarachchi, Esra Talu, Marjorie L. Longo, Paul A. Dayton, Abraham
P. Lee, “On-Chip Generation of Lipid-Stabilized
Microbubble Contrast Agents for Echocardiography”,
8th Annual UC Systemwide Bioengineering Symposium at UCSF,
pp. 47-48, California, USA, June 15-17, 2007 *Podium
Talk Award*
- Esra Talu, Kanaka Hettiarachchi, Abraham P. Lee, Robert L. Powell, Paul Dayton, Margie Longo, “A Novel Production Method for Lipid-Stabilized Monodisperse Ultrasound Contrast Agents”, AIChE 2006 Annual Meeting, San Francisco, California, USA, November 12-17, 2006
- Kanaka
Hettiarachchi, Esra Talu, Marjorie L. Longo, Paul A. Dayton, Abraham
P. Lee, “Controlled Microfluidic Generation of Lipid
Shell-Based Perfluorocarbon Microbubbles for use as Ultrasound
Contrast Agents”, The Tenth International Conference
on Miniaturized Systems for Chemistry and Life Sciences (uTAS
2006),
pp.
822-824, Tokyo, Japan, November
5-9, 2006
- Esra
Talu, Kanaka Hettiarachchi,
Abraham P. Lee, Marjorie L. Longo, Paul A. Dayton, “Lipid-stabilized
Monodisperse Microbubbles Produced by Flow Focusing for Use as
Ultrasound Contrast Agents”, IEEE International
Ultrasonics Symposium, pp.
1568-1571, Vancouver, Canada, October 5, 2006
- Kanaka Hettiarachchi,
Paul Dayton, Abraham P. Lee, "Formulation of Monodisperse
Contrast Agents in Microfluidic Systems for Ultrasonic Imaging",
Proc.
of IEEE-Microtechnologies in Medicine and Biology, pp. 230-232,
Okinawa, Japan, May 9-12, 2006
- Huiwei Wu,
Alice Koski, Kanaka Hettiarachchi, Anderson Yun, Nigel Parkinson,
Donald E. Schmidt, Jr. and Qifeng Xue, "Gram
Scale Preparative Reversed Phase High-Performance Liquid Chromatography-Mass
Spectrometry System for High Throughput Purification to Support
Drug Discovery", Theravance, Inc., 46th Rocky
Mountain Conference on Analytical Chemistry (ACS), Colorado,
USA, August 2-4, 2004
Interests:
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