Kanaka Hettiarachchi

PhD Student
Department of Biomedical Engineering, UC Irvine

Research Interests:

• Microfluidics & BioMEMS
• Ultrasound Contrast Agents
• Drug Delivery
• Liposome Technology
• Biosensors
• DNA Extraction & Sorting

Contact Information:

Education:

• M.S., Biomedical Engineering, University of California, Irvine
• B.S., Bioengineering, University of California, San Diego

Journal Publications:

• Esra Talu, Kanaka Hettiarachchi, Robert L. Powell, Abraham. P. Lee, Paul A. Dayton, Marjorie L. Longo, “Maintaining Monodispersity in a Microbubble Population Formed by Flow Focusing”, Langmuir, In Press 2007

• Esra Talu, Kanaka Hettiarachchi, Shukui Zhao, Robert L. Powell, Abraham. P. Lee, Marjorie L. Longo, Paul A. Dayton, “Tailoring the size distribution of ultrasound contrast agents: A possible method for improving sensitivity in molecular imaging”, Molecular Imaging, In Press 2007

• Kanaka Hettiarachchi, Esra Talu, Marjorie L. Longo, Paul A. Dayton, and Abraham P. Lee*, "On-chip generation of microbubbles as a practical technology for manufacturing contrast agents for ultrasonic imaging", Lab on a Chip, vol. 7(4), pp. 463-468, 2007

• Yung-Chieh Tan, Kanaka Hettiarachchi, Maria Siu, Yen-Ru Pan, and Abraham
  Phillip Lee, "Controlled Microfluidic Encapsulation of Cells, Proteins and
  Microbeads in Lipid Vesicles", Journal of the American Chemical Society, vol. 128(17), pp. 5656 - 5658, 2006

Conference Publications:

• Kanaka Hettiarachchi, Esra Talu, Marjorie L. Longo, Paul A. Dayton, Abraham P. Lee, “Manufacture of Dual-Layer Microbubble Lipospheres as Drug Delivery Vehicles in Microfluidic Devices”, The Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS 2007), pp. 191-193, Paris, France, October 7-11, 2007 *Best Poster Award*

• Kanaka Hettiarachchi, Esra Talu, Marjorie L. Longo, Paul A. Dayton, Abraham P. Lee, “Multi-Array Flow-Focusing Devices to Accelerate Production of Microbubbles for Contrast-Enhanced Ultrasound Imaging”, The Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS 2007), pp. 664-666, Paris, France, October 7-11, 2007

• Kanaka Hettiarachchi, Esra Talu, Marjorie L. Longo, Paul A. Dayton, Abraham P. Lee, “On-Chip Generation of Lipid-Stabilized Microbubble Contrast Agents for Echocardiography”, 8th Annual UC Systemwide Bioengineering Symposium at UCSF, pp. 47-48, California, USA, June 15-17, 2007 *Podium Talk Award*

• Kanaka Hettiarachchi, Esra Talu, Marjorie L. Longo, Paul A. Dayton, Abraham P. Lee, “Controlled Microfluidic Generation of Lipid Shell-Based Perfluorocarbon Microbubbles for use as Ultrasound Contrast Agents”, The Tenth International Conference on Miniaturized Systems for Chemistry and Life Sciences (uTAS 2006), pp. 822-824, Tokyo, Japan, November 5-9, 2006

• Esra Talu, Kanaka Hettiarachchi, Abraham P. Lee, Marjorie L. Longo, Paul A. Dayton, “Lipid-stabilized Monodisperse Microbubbles Produced by Flow Focusing for Use as Ultrasound Contrast Agents”, IEEE International Ultrasonics Symposium, pp. 1568-1571, Vancouver, Canada, October 5, 2006

• Kanaka Hettiarachchi, Paul Dayton, Abraham P. Lee, "Formulation of Monodisperse Contrast Agents in Microfluidic Systems for Ultrasonic Imaging", Proc. of IEEE-Microtechnologies in Medicine and Biology, pp. 230-232, Okinawa, Japan, May 9-12, 2006

• Huiwei Wu, Alice Koski, Kanaka Hettiarachchi, Anderson Yun, Nigel Parkinson, Donald E. Schmidt, Jr. and Qifeng Xue, "Gram Scale Preparative Reversed Phase High-Performance Liquid Chromatography-Mass Spectrometry System for High Throughput Purification to Support Drug Discovery", Theravance, Inc., 46th Rocky Mountain Conference on Analytical Chemistry (ACS), Colorado, USA, August 2-4, 2004

Interests:

• Tennis, Hiking, Plants, Painting & Photography: http://www.kanakasart.com